产品货号：
Z37599
中文名称：
GAPDH抗体
英文名称：
Anti-GAPDH Antibody (Clone#1653CT614.35.51)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GAPDH Antibody (Clone#1653CT614.35.51) |
| 指标别名 | G3PD;GAPD;GAPDH;OK/SW cl.12 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,IHC |
| 基因名称 | GAPDH |
| 克隆号 | 1653CT614.35.51 |
| 抗体来源 | Mouse |
| 免疫原 | This GAPDH antibody is generated from a mouse immunized with a recombinant protein between 43-335 amino acids from human GAPDH. |
| 计算分子量 | 36kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,thereby playing a role in glycolysis and nuclear functions,respectively.Participates in nuclear events including transcription,RNA transport,DNA replication and apoptosis.Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1,HDAC2 and PRKDC.Modulates the organization and assembly of the cytoskeleton.Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate.Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. |
| Uniprot ID | P04406 |
相关搜索：GAPDH抗体，GAPDH单抗，Anti-GAPDH Antibody (Clone#1653CT614.35.51)